Antibiotic Resistance Crisis: UK Scientists Race for New Solutions: Current CDC efforts focus on four core actions to fight antibiotic resistance. Preventing infections and the spread of resistant bacteria. Tracking resistant bacteria improving antibiotic use. Promoting the use of new diagnostic tools and the development of new antibiotics.
Antibiotic Resistance Crisis: UK Scientists Race for New Solutions
Abstract
Controlling antibiotic-resistant bacteria calls for widespread adoption of antibiotic stewardship programs; better diagnosis, tracking and prescribing practices; optimized therapeutic regimens; prevention of infection transmission; and new drugs.
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Introduction
The rapid emergence of resistant bacteria is occurring worldwide, endangering the efficacy of antibiotics implementation of recommended steps, such as the adoption of antibiotic stewardship programs improving diagnosis, tracking and prescribing practices, optimizing therapeutic regimens and preventing infection transmission are expected to be effective in managing this crisis.
Managing the Antibiotic Resistance Crisis
Recommended Steps To Reduce Antibiotic Resistance
The Centers for Disease Control and Prevention, as well as other organizations and experts, recommends various steps that health care practitioners and facilities can pursue to reduce antibiotic resistance, like adopting an antibiotic stewardship program and improving diagnosis, tracking and prescribing practices.
Adopt Antibiotic Stewardship Programs
Antibiotic stewardship programs guide all prescribers in administering antibiotics correctly. Antibiotic stewardship involves committing to use antibiotics only when needed, choosing the proper drug and administering the medication at the appropriate dose and duration in every case.
Antibiotic stewardship programs have been shown to improve patient care, shorten hospital stays, and reduce health care facilities’ Pharmacy costs. A review of 24 studies published from 1996 to 2010 demonstrated that antibiotic stewardship programs achieved an 11% to 38% reduction in defined daily doses per 1,000 patient days.
Improve Prescribing practices
Incorrect prescribing practices, such as the unnecessary use or wrong choice of an antibiotic agent, are prevalent in both inpatient and outpatient settings. A post-prescription review of multiple hospitals in 10 U.S states identified opportunities to improve antibiotic prescribing in 37% of the scenarios, often through the use of diagnostic tests, improved documentation of symptoms and optimization of antimicrobial therapy.
In other cases, patients may demand treatment for conditions, such as colds, when antibiotics are not needed and will not help since viruses cause most colds. Data suggest that HCPs may be too willing to satisfy such patients’ expectations fr an antibiotic prescription.
Optimize Therapeutic Regimens
Antibiotics are generally prescribed according to a fixed regimen that involves a specific dose, so frequency and length of treatment like regimens typically last five to seven days, although many last 14 days or longer.
Availability of New Antibiotics
The development of new antibiots by the pharmaceutical industry a strategy that had been effective at combating resistant bacteria in the past, had essentially stalled due to economic na regulatory obstacles if the 18 largest pharmaceutical companies, 15 abandoned the antibiotic filed Mergers between pharmaceutical companies have also substantially reduced the number and diversity of research teams.
Developing Antibiotic resistance: A Timeline of key Events
Dates are based on the early reports of resistance in the literature. In the case of padrug resistance, the date based upon reports are transmission or outbreaks.
Benefits of antibiotics:
Antibiotics have not only saved patients livesm, they have played a pivotal role in achieving major advances in medicine and surgery they have successfully prevented or treated infections that avccan get in patients who are getting chemotherapy treatm, events; wo have chronic diseases such as diabetes, end-stage renal disease or rheumatoid arthritis; or who have had complex surgeries such as organ transplants joint surgery.
Cause of the Antibiotic Resistance Crisis
Overuse: As early as 1945, Sir Alexander raised the alarm regarding antibiotic overuse when he warned that the public would demand then will begin an era of abuses. The overuse of antibiotics drives the evolution of resistance.
- Antibiotic Prescriptions per 1,000 Persons Of all Ages According to State 2010
- Inappropriate Prescribing
- Extensive Agricultural Use
- Availability of Few New Antibiotics
- Names of Antibacterial New Drug Application Approvals Versus Year Intervals
- Regulatory Barries
Conclusion
In this article, we discussed the Antibiotic Resistance Crisis: UK Scientists Race for New Solutions. Current CDC efforts focus on four core actions to fight antibiotic resistance. Preventing infections and the spread of resistant bacteria. The Centers for Disease Control and Prevention, as well as other organizations and experts, recommends various steps that health care practitioner